Uday Bandyopadhyay obtained BSc (1985) and Post-graduate Degree from Calcutta University, Kolkata. He was awarded PhD (1994), in the area of gastric pathophysiology and cell biology. He worked as a Post-doctoral Research Fellow (1995-96) with Professor R Barouki, INSERM-U 99, Paris, France, studying the regulation of aspartate aminotransferase gene expression in hepatoma cells. He then worked as a Post-doctoral Research Fellow (1996-97) with Professor Andreas H Guse in the Department of Physiological Chemistry, University of Hamburg, Germany, studying inositol pentakisphosphate metabolizing enzyme as well as regulation of Ca2+ signaling in T-lymphocytes. On return to India, he initially joined as pool officer at CSIR-Indian Institute of Chemical Biology, Kolkata and then moved to CSIR-Central Drug Research Institute, Lucknow as faculty of the department of biochemistry (2002-2006). In 2006, he again joined CSIR-Indian Institute of Chemical Biology, Kolkata in the department of infectious diseases and immunology as a senior faculty.
Academic and Research Achievements: Dr Bandyopadhyay's research focused in the area of cell biology with particular reference to mitochondrial oxidative stress in relation to initiation of gastric ulcer/gastropathy by commonly prescribed non-steroidal anti-inflammatory drug (NSAIDs). His studies were aimed to define the molecular basis as well as players of developing mitochondrial oxidative stress and gastric mucosal cell apoptosis as result of electron transport chain defect induced by NSAIDs. He proved that correction of mitochondrial pathology and subsequent inhibition of gastric mucosal cell apoptosis is a novel rational for antiulcer therapy. Besides outstanding contribution in the field of gastric pathophysiology, he also made a remarkable contribution in the field of malaria and established that the development of oxidative stress in malaria parasite is a novel way to develop new antimalarial by designing new redox active molecule. He characterized an Alba-family protein from human malaria parasite Plasmodium falciparum and reported its binding to the telomeric and subtelomeric regions as well as to var gene promoter to control gene expression. He has published over 75 research articles in different national and international journals of repute. He has also published several Indian, USA, European and Japanese patents.
Other Contributions: He has served on the Editorial Board of World Journal of Gastrointestinal Pathophysiology.
Awards and Honours: Dr Bandyopadhyay is a recipient of several awards and honours including Humboldt Fellowship (Alexander Von Humboldt Foundation, Germany, 1996), Professor R. C. Shah Memorial Award ( 96th Indian Science Congress, 2009), Professor A. N. Bhaduri Memorial Award ( Society of Biological Chemist (India), 2012) and J. C. Bose National Fellowship (Department of Science and Technology, 2015). He is a Fellow of the National Academy of Sciences (India), Allahabad, Fellow of Indian Academy of Sciences, Bangalore, Fellow of Indian National Science Academy, New Delhi and Fellow of West Bengal Academy of Science and Technology, Kolkata.