Dr Anirban Basu’s pre-doctoral studies were at School of Life Sciences, Viswa Bharati University, Santiniketan, doctoral work at CSIR-Indian Institute of Chemical Biology, Kolkata and post-doctoral work at Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Dr. Basu joined National Brain Research Center in 2004. Since then he has been working on understanding how neurotropic viruses cause abnormality in brain function and development. The major emphasis of his research is directed towards discovering therapeutic strategies against neuro-inflammatory and neuro-degenerative disorders. So far his work has not only highlighted the importance of neuro-immune response in regulating viral infection of the brain, but his work has been instrumental in filling the void needed to bridge the gap between translational and basic research centering infection of the brain.
Academic and Research Achievements
Dr. Basu has long been interested in curing diseases of the nervous system. His current research is focused on identifying the role of microglia and neural stem/progenitor cells in the healthy and diseased central nervous system. The group of people who currently work with him is testing strategies to develop disease modifying therapy by abrogating inflammation in CNS disorders. Besides studying fundamental aspects of virus induced neuropathology Dr Basu always keen to do translational research to develop newer generation of therapy for Japanese Encephalitis and other neurotropic viruses. Based upon pre-clinical study undertaken in Dr Basu’s laboratory at National Brain Research Center, a Phase II clinical trial has been completed at King George Medical University (KGMU), Lucknow, where minocycline has been used as a therapy for Japanese Encephalitis patients and the patients with Acute Encephalitis Syndrome (AES). It has been observed in this trial that Minocycline has some beneficial effect in patients especially in those patients who survive the initial days in hospital. These findings could form the basis for planning a larger study and possibly including minocycline in the management of AES and JE.
So far Dr Basu has trained 5 Masters students, 10 PhD students and 11 postdocs, and numerous short term and long term research trainees in his lab.
Dr Basu sits on the editorial boards of several journals of repute which includes but not restricted to the Journal of Neurochemistry, Scientific Reports, Journal of Neuroinflammation,, Frontiers in Molecular Neuroscience, and Metabolic Brain Diseases. Dr Basu is also a faculty member in the Faculty of 1000 in the section Neurological Disorders (Infectious Diseases of the Nervous System).
Awards and Honours
Dr Basu is the recipient of National Bioscience Award for Career Development (2010), Vasvik Industrial Research Award (2011), Dr. J.B. Srivastav Oration Award (2011), Rajib Goyal Prize (2012), NASI- Reliance Industries Platinum Jubilee Award (2013), Tata Innovation Fellowship (2015) from the Department of Biotechnology, Senior Scientist Oration Award (2015), from the Indian Immunology Society, Sreenivasaya Memorial Award (2017) of Society of Biological Chemist (India), and Prof S S Katiyar Endowment Lecture of The Indian Science Congress Association (ISCA)-2018
He is also an elected Fellow of the National Academy of Sciences (2011), West Bengal Academy of Science and Technology (2012), and Indian Academy of Sciences (2018).