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  Soumen Basak

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Name Dr Soumen Basak
(Dr Soumen Basak)
FNA ID P22-1899
Address Staff Scientist VI and the Laboratory Head, Systems Immunology Laboratory, National Institute of Immunology,
City New Delhi
Pin Code 110067
Country India
Gender Male
Specialization Immunology, Cancer Biology, Systems Biology, Virology, Cell Signaling
Service in the Council
Qualification PhD
Membership FASc, FNASc, FNA
  Year of Election 2022  
E-mail sobasak@nii.ac.in
Personal Website

Extracellular cues engage discrete cell signaling pathways to activate specific sets of transcription factors, which trigger distinct gene-expression programs. However, these pathways are known to be physically and functionally interlinked within the cellular network. More so, in their anatomic niche, mammalian cells receive signals from a variety of stimuli that generate plausible crosstalks between concomitantly activated pathways. Combining biochemistry, genetics, and computational modeling, we have been characterizing these cross-regulatory mechanisms and elucidating their role in physiology and diseases. We are particularly investigating how the so-called “immune-organogenic” noncanonical NF-κB pathway crosstalks with inflammatory canonical NF-κB signaling and the anti-viral type1- interferon axis.

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